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Article

Variant Histone H2afv reprograms DNA methylation during early zebrafish development.

Epigenetics - 1 Sept 2017

Madakashira Bhavani, Corbett Laura, Zhang Chi, Paoli Pier, Casement John W, Mann Jelena, Sadler Kirsten C, Mann Derek A

Abstract excerpt

The DNA methylome is re-patterned during discrete phases of vertebrate development. In zebrafish, there are 2 waves of global DNA demethylation and re-methylation: the first occurs before gastrulation when the parental methylome is changed to the zygotic pattern and the second occurs after formation of the embryonic body axis, during organ specification. The occupancy of the histone variant H2A.Z and regions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29099280
DOI: 10.1080/15592294.2017.1359382
PMCID: PMC5739095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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