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Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming.

Cell - 22 Feb 2018

Murphy Patrick J, Wu Shan Fu, James Cody R, Wike Candice L, Cairns Bradley R

Abstract excerpt

The fate and function of epigenetic marks during the germline-to-embryo transition is a key issue in developmental biology, with relevance to stem cell programming and transgenerational inheritance. In zebrafish, DNA methylation patterns are programmed in transcriptionally quiescent cleavage embryos; paternally inherited patterns are maintained, whereas maternal patterns are reprogrammed to match the paternal....

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Identifiers

PMID: 29456083
DOI: 10.1016/j.cell.2018.01.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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