Article

Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

2022-03-04

Abstract excerpt

During metazoan development, the dramatic potency change from germline to embryos raises an important question regarding how the new life cycle is reset. Here, we report a tightly regulated epigenome landscape change from the parental germline to embryos in C. elegans . The epigenome is enriched with histone H3 in early-stage germ cells but switches to a histone variant H3.3-enriched epigenome in the mature egg....

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Literature Corpus work: 33d0cb18-467b-5459-acf3-a37e32057e52
DOI: 10.1101/2022.03.01.482564

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