Article
Allelic reprogramming of the histone modification H3K4me3 in early mammalian development.
Nature - 22 Sept 2016
Zhang Bingjie, Zheng Hui, Huang Bo, Li Wenzhi, Xiang Yunlong, Peng Xu, Ming Jia, Wu Xiaotong, Zhang Yu, Xu Qianhua, Liu Wenqiang, Kou Xiaochen, Zhao Yanhong, He Wenteng, Li Chong, Chen Bo, Li Yuanyuan, Wang Qiujun, Ma Jing, Yin Qiangzong, Kee Kehkooi, Meng Anming, Gao Shaorong, Xu Feng, Na Jie, Xie Wei
Abstract excerpt
Histone modifications are fundamental epigenetic regulators that control many crucial cellular processes. However, whether these marks can be passed on from mammalian gametes to the next generation is a long-standing question that remains unanswered. Here, by developing a highly sensitive approach, STAR ChIP-seq, we provide a panoramic view of the landscape of H3K4me3, a histone hallmark for transcription...
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