Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos

7 Jan 2025

Abstract excerpt

In the germ line and during early embryogenesis, DNA methylation (DNAme) undergoes global erasure and re-establishment to support germ cell and embryonic development. While DNAme acquisition during male germ cell development is essential for setting genomic DNA methylation imprints, other intergenerational roles for paternal DNAme in defining embryonic chromatin are unknown. Through conditional gene deletion of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Prenatal Screening and Diagnostics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39774947
DOI: 10.1038/s41467-024-55441-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryosPMID 39774947Read ↗

DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryosSemantic proximity Read ↗

Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo.Semantic proximity Read ↗

Genome-Wide Analysis of DNA Methylation Dynamics during Early Human DevelopmentSemantic proximity Read ↗

Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo.Semantic proximity Read ↗

Site-specific DNA demethylation during spermatogenesis presets the sites of nucleosome retention in mouse spermSemantic proximity Read ↗

Plasticity in Dnmt3L-dependent and -independent modes of de novo methylation in the developing mouse embryo.Semantic proximity Read ↗

Establishment and Functions of DNA Methylation in the GermlineSemantic proximity Read ↗

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination.Semantic proximity Read ↗

Preventing CpG island hypermethylation in oocytes safeguards mouse developmentSemantic proximity Read ↗

Targets and dynamics of promoter DNA methylation during early mouse development.Semantic proximity Read ↗

Conservation of DNA Methylation Programming Between Mouse and Human Gametes and Preimplantation EmbryosSemantic proximity Read ↗

Distinct H3K9me3 and DNA methylation modifications during mouse spermatogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.