Article

Enhancer-associated H3K4 methylation safeguards in vitro germline competence

2020-07-07

Abstract excerpt

<h4>SUMMARY</h4> Germline specification in mammals occurs through an inductive process whereby competent cells in the post-implantation epiblast differentiate into primordial germ cells (PGC). The intrinsic factors that endow epiblast cells with the competence to respond to germline inductive signals remain unknown. Single-cell RNA sequencing across multiple stages of an in vitro PGC-like cells (PGCLC) different...

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Literature Corpus work: c99e501e-9db4-58ea-b13d-d7eb2cd87d2d
DOI: 10.1101/2020.07.07.192427

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