Article

T cell immunity does not age in a long-lived rodent species

2018-02-02

Abstract excerpt

Numerous studies have demonstrated that the percentage of naïve T cells and diversity of T cell receptor (TCR) repertoire decrease with age, with some findings likewise suggesting that increased repertoire diversity may be associated with longer lifespan and healthy aging. In this work, we have analyzed peripheral TCR diversity from humans, mice, and blind mole-rats ( Spalax spp .)—long-lived, hypoxia- and cancer...

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Literature Corpus work: fdc82db1-73e3-55ee-b797-7566cff4cfdc
DOI: 10.1101/259374

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