Article

Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish

2020-08-21

Abstract excerpt

Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood during aging; however, little is known about repertoire aging in other immune compartments, or in species other than humans. Here, we perform the first study of immune-repertoire aging in...

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Literature Corpus work: f73c2195-5363-5225-9563-5b2d5d2b3845
DOI: 10.1101/2020.08.21.261248

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