Article

A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

2022-09-08

Abstract excerpt

Phagocytosis, the process of engulfing large particles by cells, is a multilayered biological activity driving tissue clearance and host defense. Dysregulation of phagocytosis is connected to autoimmunity, accumulation of toxic disease proteins, and increased risks for infections. Despite its importance and multiple roles, we lack a full understanding of the cellular machinery involved in executing and regulating...

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Literature Corpus work: fd8c5239-d835-58b0-9f3a-0f1dd3152807
DOI: 10.1101/2022.09.08.507072

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