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Cell surface receptors TREM2, CD14 and integrin α <sub>M</sub> β <sub>2</sub> drive sinking engulfment in phosphatidylserine-mediated phagocytosis

2022-07-31

Abstract excerpt

<h4>Summary</h4> Macrophages phagocytose and thereby eliminate a wide array of extracellular threats, ranging from antibody-coated bacteria to apoptotic cells. Precision modulation of phagocytosis has emerged as a therapeutic strategy across a range of diseases, but is limited by our incomplete understanding of how macrophages recognize, engulf, and respond to different phagocytic targets. Here, we undertook a sy...

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Literature Corpus work
a3f4df2a-ecf5-51af-85b6-568047a61c91
DOI
10.1101/2022.07.30.502145
Open publication

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Cell surface receptors TREM2, CD14 and integrin α <sub>M</sub> β <sub>2</sub> drive sinking engulfment in phosphatidylserine-mediated phagocytosisDOI 10.1101/2022.07.30.502145
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