Article

A genome-wide screen in macrophages defines host genes regulating the uptake of <i>Mycobacterium abscessus</i>

2022-12-21

Abstract excerpt

<h4>ABSTRACT</h4> The interactions between a host cell and a pathogen can dictate disease outcomes and are important targets for host-directed therapies. Mycobacterium abscessus (Mab) is a highly antibiotic resistant, rapidly growing non-tuberculous mycobacterium that infects patients with chronic lung diseases. Mab can infect host immune cells, such as macrophages, which contribute to its pathogenesis. However,...

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Literature Corpus work: e932f81e-8b0a-5e9a-a725-380ad318fc8e
DOI: 10.1101/2022.12.20.521338

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