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Article

Eat‐me signals: Keys to molecular phagocyte biology and “Appetite” control

25 Apr 2011

Abstract excerpt

Hundreds of billions of cells undergo apoptosis in our body everyday and are removed by immunologically silent phagocytosis to maintain tissue homeostasis. Impairments in phagocytosis result in autoimmune and/or degenerative diseases. Eat-me signals are the key to the recognition of extracellular cargos and the initiation of the phagocytosis process by activating phagocytic receptors and signaling cascades, and...

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PMID: 21520079
DOI: 10.1002/jcp.22815

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