Article

A spectral analysis approach to detect actively translated open reading frames in high-resolution ribosome profiling data

2015-11-13

Abstract excerpt

RNA sequencing protocols allow for quantifying gene expression regulation at each individual step, from transcription to protein synthesis. Ribosome Profiling (Ribo-seq) maps the positions of translating ribosomes over the entire transcriptome. Despite its great potential, a rigorous statistical approach to identify translated regions by means of the characteristic three-nucleotide periodicity of Ribo-seq data is...

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Literature Corpus work: fd8b23d2-0d69-558f-8a4e-12392e4effcf
DOI: 10.1101/031625

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