Article

Protein Synthesis Profiling Enables In Vivo Capture of Ribosome-Associated mRNAs in Yeast

2025-11-17

Abstract excerpt

Translation is a central control point of gene expression, linking nucleotide sequences to functional proteins. Dysregulated translation contributes to diverse diseases, underscoring the need for methods that can directly reveal which transcripts are actively translated. Ribosome profiling, the current gold standard, provides nucleotide-resolution maps of ribosome occupancy but requires laborious purification and...

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Literature Corpus work: aba09e7d-cae7-569a-a8ef-25dc9043faeb
DOI: 10.1101/2025.11.17.688896

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