Article

Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling

2015-11-13

Abstract excerpt

Accurate annotation of protein coding regions is essential for understanding how genetic information is translated into biological functions. Here we describe riboHMM, a new method that uses ribosome footprint data along with gene expression and sequence information to accurately infer translated sequences. We applied our method to human lymphoblastoid cell lines and identified 7,273 previously unannotated coding...

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Literature Corpus work: e08bc488-cfbb-5dc1-9f75-027e65c1b76b
DOI: 10.1101/031617

Open publication

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