Article

What can Ribo-seq and proteomics tell us about the non-canonical proteome?

2023-05-18

Abstract excerpt

Ribosome profiling (Ribo-seq) has proven transformative for our understanding of the human genome and proteome by illuminating thousands of non-canonical sites of ribosome translation outside of the currently annotated coding sequences (CDSs). A conservative estimate suggests that at least 7,000 non-canonical open reading frames (ORFs) are translated, which, at first glance, has the potential to expand the number...

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Literature Corpus work: 84081706-72c2-5a57-95f8-19750dc51da3
DOI: 10.1101/2023.05.16.541049

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