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Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in Candida auris , Candida albicans , Candida parapsilosis , and Candida glabrata ( Nakaseomyces glabratus )

2025-05-09

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The fungal pathogen Candida auris is of global concern due to high levels of multidrug resistance and its propensity to cause infectious outbreaks. Over 90% of isolates are resistant to fluconazole, the most commonly prescribed antifungal world-wide. Fluconazole resistance is multifactorial with many isolates carrying mutations in the gene encoding the transcriptional regulator Tac1B, leading to increased express...

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Literature Corpus work: fd460dbd-054f-5504-b976-62242ee05f9b
DOI: 10.1101/2025.05.07.652603

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Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in Candida auris , Candida albicans , Candida parapsilosis , and Candida glabrata ( Nakaseomyces glabratus )DOI 10.1101/2025.05.07.652603Read

Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in Candida auris (Candidozyma auris), Candida albicans, Candida parapsilosis, and Candida glabrata (Nakaseomyces glabratus).Semantic proximity Read

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Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in <i>Candida auris</i> , <i>Candida albicans</i> , <i>Candida parapsilosis</i> , and <i>Candida glabrata</i> ( <i>Nakaseomyces glabratus</i> )

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