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Article

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris.

mBio - 12 May 2020

Rybak Jeffrey M, Muñoz José F, Barker Katherine S, Parker Josie E, Esquivel Brooke D, Berkow Elizabeth L, Lockhart Shawn R, Gade Lalitha, Palmer Glen E, White Theodore C, Kelly Steve L, Cuomo Christina A, Rogers P David

Abstract excerpt

Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern. Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most commonly prescribed antifungal agent, and yet it remains unknown what mechanisms underpin this fluconazole resistance. To identify novel mechanisms contributing to fluconazole resistance in C. auris, fluconazole-susceptible C. auris clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32398311
DOI: 10.1128/mBio.00365-20
PMCID: PMC7218281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris.PMID 32398311Read ↗

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