Article

Broad sensitivity of <i>Candida auris</i> strains to quinolones and mechanisms of resistance

2023-02-17

Abstract excerpt

The fungal pathogen Candida auris represents a severe threat to hospitalized patients. Its resistance to multiple classes of antifungal drugs and ability to spread and resist decontamination in health-care settings make it especially dangerous. We screened 1,990 clinically approved and late-stage investigational compounds for the potential to be repurposed as antifungal drugs targeting C. auris and narrowed our...

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Literature Corpus work: 86054e74-04d6-5611-bbaf-e6365c07c355
DOI: 10.1101/2023.02.16.528905

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