Article

Integrative tissue-specific functional annotations in the human genome provide novel insights on many complex traits and improve signal prioritization in genome wide association studies

2015-10-06

Abstract excerpt

Extensive efforts have been made to understand genomic function through both experimental and computational approaches, yet proper annotation still remains challenging, especially in non-coding regions. In this manuscript, we introduce GenoSkyline, an unsupervised learning framework to predict tissue-specific functional regions through integrating high-throughput epigenetic annotations. GenoSkyline successfully id...

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Literature Corpus work: 498a82cf-d6d7-5fa2-ae0d-e63ad1ca3b55
DOI: 10.1101/028464

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