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Modelling the Dynamics of T-Cell Development in the Thymus

2021-01-19

Abstract excerpt

The thymus hosts the development of a specific type of adaptive immune cells called T cells. T cells orchestrate the adaptive immune response through recognition of antigen by the highly variable T-cell receptor (TCR). T-cell development is a tightly coordinated process comprising lineage commitment, somatic recombination of Tcr gene loci and selection for functional, but non-self-reactive TCRs, all interspersed w...

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Literature Corpus work
fd1f73a7-d55a-5d86-b00a-d72ea4d99513
DOI
10.20944/preprints202101.0388.v1
Open publication

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Modelling the Dynamics of T-Cell Development in the ThymusDOI 10.20944/preprints202101.0388.v1
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