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Article

Conventional and Computational Flow Cytometry Analyses Reveal Sustained Human Intrathymic T Cell Development From Birth Until Puberty.

Frontiers in immunology - 1 Jan 2020

Lavaert Marieke, Valcke Brecht, Vandekerckhove Bart, Leclercq Georges, Liang Kai Ling, Taghon Tom

Abstract excerpt

The thymus is the organ where subsets of mature T cells are generated which subsequently egress to function as central mediators in the immune system. While continuously generating T cells even into adulthood, the thymus does undergo involution during life. This is characterized by an initial rapid decrease in thymic cellularity during early life and by a second age-dependent decline in adulthood. The thymic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32849574
DOI: 10.3389/fimmu.2020.01659
PMCID: PMC7417369

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