Article

DNA-PK facilitates HIV transcription by regulating the activity of RNA polymerase II and the recruitment of transcription machinery at HIV LTR

2017-08-10

Abstract excerpt

<h4>ABSTRACT</h4> Despite the use of highly effective antiretroviral therapy (HAART), the presence of latent or transcriptionally silent proviruses prevents cure and eradication of HIV infection. These transcriptionally silent proviruses are well protected from both the immune system and HAART regimens. Thus, in order to tackle the problem of latent HIV reservoirs, it is a prerequisite to define all the pathways...

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Literature Corpus work: fcaa6441-0213-59b7-9666-4048b42b407c
DOI: 10.1101/174573

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