Article

Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

2020-01-07

Abstract excerpt

<h4>SUMMARY</h4> Viruses must effectively remodel host cellular pathways to replicate and evade immune defenses, and they must do so with limited genomic coding capacity. Targeting post-translational modification (PTM) pathways provides a mechanism by which viruses can broadly and rapidly transform a hostile host environment into a hospitable one. We used quantitative proteomics to measure changes in two PTM type...

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Literature Corpus work: d9ec7b30-a9e5-53d4-844d-9a2ac7e64204
DOI: 10.1101/2020.01.06.896365

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