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Article

Maternal separation disrupts noradrenergic control of adult coping behaviors

2025-03-10

Abstract excerpt

Early life stress (ELS) in humans and preclinical rodent models profoundly impacts the brain and correlates with negative affective behaviors in adulthood. The locus coeruleus (LC), a stress-responsive brainstem nucleus that supplies most of the brain with norepinephrine (NE), is known to modulate negative affect. Here we used repeated maternal separation stress (MSS) to investigate the impact of ELS on the LC and...

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Literature Corpus work
fc769ea3-ab51-5c17-bd94-a83ebdc49e2e
DOI
10.1101/2025.03.09.642152
Open publication

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Maternal separation disrupts noradrenergic control of adult coping behaviorsDOI 10.1101/2025.03.09.642152
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