Article

Hyperactivity of the Amygdala Mediates Depressive-Like Phenotypes and Decreased Serotonin Release

2025-03-11

Abstract excerpt

Clinical and preclinical studies have consistently demonstrated a correlation between hyperactivity of the amygdala and the onset of depression. However, the underlying mechanisms influencing serotonin levels a critical neurotransmitter implicated in depression and a primary target for selective serotonin reuptake inhibitors (SSRIs) remain inadequately understood. In this study, we employed a restrained inescapabl...

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Literature Corpus work: e10c1d5c-5d9b-5c3b-bdf7-700ed072dfaa
DOI: 10.1101/2025.03.10.642393

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