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Article

Early life stress modulates behavioral sensitivity to alcohol and promotes escalation of alcohol drinking

2025-06-28

Abstract excerpt

<h4>ABSTRACT</h4> Adverse childhood experiences significantly increase the risk of developing alcohol use disorder (AUD) in adulthood. We used a model of combined limited bedding/nesting and maternal separation (LBN+MS) in C57BL/6J background mice to investigate how early life stress (ELS) modulates behavioral sensitivity to alcohol, long-term alcohol drinking patterns, and the effects of alcohol on social behavi...

Identifiers and source

Literature Corpus work
03277eb0-8f08-57c2-83fd-00a6b8365f1e
DOI
10.1101/2025.06.27.661986
Open publication

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Early life stress modulates behavioral sensitivity to alcohol and promotes escalation of alcohol drinkingDOI 10.1101/2025.06.27.661986
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