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Article

Repeated neonatal handling with maternal separation permanently alters hippocampal GABAA receptors and behavioral stress responses.

Proceedings of the National Academy of Sciences of the United States of America - 14 Oct 2003

Hsu Fu-Chun, Zhang Guo-Jun, Raol Yogendra Sinh H, Valentino Rita J, Coulter Douglas A, Brooks-Kayal Amy R

Abstract excerpt

Increasing evidence suggests that postnatal events, such as handling or maternal separation, can produce long-term changes in brain function. These are often expressed as changes in the profile of endocrine or behavioral responses to stress. Changes in gamma-aminobutyric acid type A receptors (GA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14530409
DOI: 10.1073/pnas.2131679100
PMCID: PMC218738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14530409-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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