Article

Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader–Willi syndrome

2020-07-08

Abstract excerpt

<title>Abstract</title> Background: Prader–Willi syndrome (PWS) is a neurodevelopmental disorder characterized by multiple respiratory, cognitive, endocrine, and behavioral symptoms, such as central apnea, intellectual disabilities, exaggerated stress responses, and temper tantrums. The locus coeruleus noradrenergic system (LC-NE) modulates a diverse range of behaviors, including arousal, learning, pain modula...

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Literature Corpus work: 1b55e9e6-3889-5ace-87b6-77f797b0f101
DOI: 10.21203/rs.2.24808/v3

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