Article

Factorbook: an Updated Catalog of Transcription Factor Motifs and Candidate Regulatory Motif Sites

2021-10-12

Abstract excerpt

<h4>ABSTRACT</h4> The human genome contains roughly 1,600 transcription factors (TFs) (1), DNA-binding proteins recognizing characteristic sequence motifs to exert regulatory effects on gene expression. The binding specificities of these factors have been profiled both in vitro , using techniques such as HT-SELEX (2), and in vivo , using techniques including ChIP-seq (3, 4). We previously developed Factorbook,...

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Literature Corpus work: 375ab983-f4fa-57f1-8e19-a533e7526c70
DOI: 10.1101/2021.10.11.463518

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