Back to search

Article

In vitro exposure to non-antipseudomonal antibiotics (NAPA) induces <i>Pseudomonas aeruginosa</i> resistance to antipseudomonal antibiotics (APA)

2026-02-16

Abstract excerpt

<h4>Background</h4> Pseudomonas aeruginosa readily evolves antimicrobial resistance through regulatory plasticity and stress-adaptive pathways. Clinically, antibiotics lacking intrinsic antipseudomonal activity are often favored with the assumption that they avoid selective pressure on P. aeruginosa . Whether subinhibitory exposure to such “non-antipseudomonal antibiotics” (NAPA) can nevertheless select for cano...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fb70f913-e8d4-506a-afaf-5857eba958d7
DOI
10.64898/2026.02.13.705873
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
In vitro exposure to non-antipseudomonal antibiotics (NAPA) induces <i>Pseudomonas aeruginosa</i> resistance to antipseudomonal antibiotics (APA)DOI 10.64898/2026.02.13.705873
In vitro exposure to non-antipseudomonal antibiotics (NAPA) induces Pseudomonas aeruginosa resistance to antipseudomonal antibiotics (APA).Semantic proximity
Evolution under low antibiotic concentrations: a risk for the selection of <i>Pseudomonas aeruginosa</i> multidrug resistant mutants in natureSemantic proximity
Rapid evolution drives the rise and fall of carbapenem resistance during an acute <i>Pseudomonas aeruginosa</i> infectionSemantic proximity
Multi-omics profiling of cross-resistance between ceftazidime-avibactam and meropenem identifies common and strain-specific mechanisms in <i>Pseudomonas aeruginosa</i> clinical isolatesSemantic proximity
Bacterial defenses against a natural antibiotic promote collateral resilience to clinical antibioticsSemantic proximity
A large-scale comparison shows that genetic changes causing antibiotic resistance in experimentally evolved <i>Pseudomonas aeruginosa</i> predict those in naturally evolved bacteriaSemantic proximity
Evolutionary trade-offs between antimicrobial resistance and virulence in <i>Pseudomonas aeruginosa</i>Semantic proximity
Targeting efflux pumps prevents the multi-step evolution of high-level resistance to fluoroquinolone in Pseudomonas aeruginosaSemantic proximity
Evolution of Antibiotic Tolerance Shapes Resistance Development in Chronic Pseudomonas aeruginosa Infections.Semantic proximity
Heterogeneity during induction of resistance delays <i>Pseudomonas aeruginosa</i> recovery from antibiotic exposuresSemantic proximity
High-level ciprofloxacin resistance in <i>Pseudomonas aeruginosa</i> is associated with genomic adaptation, collateral antibiotic susceptibility, and physiological trade-offsSemantic proximity
R-pyocin-mediated selection reverses pan-drug resistance in <i>Pseudomonas aeruginosa</i>Semantic proximity
Select a neighboring publication to make it the new centre.