Article

Heterogeneity during induction of resistance delays <i>Pseudomonas aeruginosa</i> recovery from antibiotic exposures

2024-09-22

Abstract excerpt

Typical antibiotic susceptibility testing (AST) of microbial samples is performed in homogeneous cultures in batch environments, which does not account for the highly heterogeneous and dynamic nature of antibiotic responses. The most common mutation found in P. aeruginosa lineages evolved during chronic infections in the human lung, a loss of function of repressor MexZ, increases basal levels of multidrug efflux...

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Literature Corpus work: d3912cf9-f1c3-5ee0-be55-a6a62d6147aa
DOI: 10.1101/2024.09.20.614194

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