Article

Rapid evolution drives the rise and fall of carbapenem resistance during an acute <i>Pseudomonas aeruginosa</i> infection

2020-08-10

Abstract excerpt

It is well established that antibiotic treatment selects for resistance in pathogenic bacteria. However, the evolutionary responses of pathogen populations to antibiotic treatment during infections remain poorly resolved, especially in acute infections. Here we map the evolutionary responses to treatment in high definition through genomic and phenotypic characterization of >100 isolates from a patient with P. aer...

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Literature Corpus work: 462d8b06-9e87-50f7-af4a-78f6f8f873e4
DOI: 10.1101/2020.08.10.243741

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