Article
In vitro exposure to non-antipseudomonal antibiotics (NAPA) induces Pseudomonas aeruginosa resistance to antipseudomonal antibiotics (APA).
The Journal of antimicrobial chemotherapy - 5 May 2026
Lasry David, Harrison Luke B, Bamba Reggie, Corsini Rachel, Yansouni Cedric P, Cheng Matthew P, Lee Todd C, Lawandi Alexander
Abstract excerpt
BACKGROUND: Pseudomonas aeruginosa readily evolves antimicrobial resistance through regulatory plasticity and stress-adaptive pathways. Clinically, antibiotics lacking intrinsic antipseudomonal activity are often favoured with the assumption that they avoid selective pressure on P. aeruginosa. Whether subinhibitory exposure to such 'non-antipseudomonal antibiotics' (NAPA) can nevertheless select for canonical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.