Article

Evolution under low antibiotic concentrations: a risk for the selection of <i>Pseudomonas aeruginosa</i> multidrug resistant mutants in nature

2021-04-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Antibiotic pollution of non-clinical environments might have a relevant impact on human health if resistant pathogens are selected. However, this potential risk is often overlooked, since drug concentrations in nature are usually below their minimal inhibitory concentrations (MICs). Albeit, antibiotic resistant bacteria can be selected even at sub-MIC concentrations, in a ra...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c9e9f44f-b661-5ccf-a5f0-8742948fcd0a
DOI: 10.1101/2021.04.21.440750

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evolution under low antibiotic concentrations: a risk for the selection of <i>Pseudomonas aeruginosa</i> multidrug resistant mutants in natureDOI 10.1101/2021.04.21.440750Read

Evolution under low antibiotic concentrations: a risk for the selection of Pseudomonas aeruginosa multidrug‐resistant mutants in natureSemantic proximity Read

Low Ciprofloxacin Concentrations Select Multidrug-Resistant Mutants Overproducing Efflux Pumps in Clinical Isolates of Pseudomonas aeruginosaSemantic proximity Read

In vitro exposure to non-antipseudomonal antibiotics (NAPA) induces <i>Pseudomonas aeruginosa</i> resistance to antipseudomonal antibiotics (APA)Semantic proximity Read

Evolution of Habitat-Dependent Antibiotic Resistance in Pseudomonas aeruginosa.Semantic proximity Read

Evolutionary trade-offs between antimicrobial resistance and virulence in <i>Pseudomonas aeruginosa</i>Semantic proximity Read

Mutation-driven evolution of <i>Pseudomonas aeruginosa</i> in the presence of either ceftazidime or ceftazidime/avibactamSemantic proximity Read

The role of antibiotics and antibiotic resistance in nature.Semantic proximity Read

A large-scale comparison shows that genetic changes causing antibiotic resistance in experimentally evolved <i>Pseudomonas aeruginosa</i> predict those in naturally evolved bacteriaSemantic proximity Read

The Pseudomonas aeruginosa Resistome: Permanent and Transient Antibiotic Resistance, an Overview.Semantic proximity Read

Rapid evolution drives the rise and fall of carbapenem resistance during an acute <i>Pseudomonas aeruginosa</i> infectionSemantic proximity Read

Evolutionary landscapes of Pseudomonas aeruginosa towards ribosome-targeting antibiotic resistance depend on selection strength.Semantic proximity Read

Adaptive resistance to antibiotics in bacteria: a systems biology perspectiveSemantic proximity Read