Article

Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease

2021-09-23

Abstract excerpt

The purpose of our study is to understand the role of the Ralbp1 gene in oxidative stress (OS), mitochondrial dysfunction and cognition in Alzheimer’s disease (AD) pathogenesis. The Ralbp1 gene encodes the 76 kDa protein Rlip ( aka RLIP76). Previous studies have revealed its role in OS-related cancer. However, Rlip is transcriptionally regulated by EP300 , a CREB-binding protein that is important for synaptic pl...

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Literature Corpus work: fb543e5d-743c-55ed-a9dc-ccc4e38a60ec
DOI: 10.1101/2021.09.20.461132

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