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RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease

10 Nov 2021

Abstract excerpt

The purpose of our study is to understand the role of the RALBP1 gene in oxidative stress (OS), mitochondrial dysfunction and cognition in Alzheimer’s disease (AD) pathogenesis. The RALPB1 gene encodes the 76 kDa protein RLIP76 (Rlip). Rlip functions as a stress-responsive/protective transporter of glutathione conjugates (GS-E) and xenobiotic toxins. We hypothesized that Rlip may play an important role in...

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PMID: 34831336
DOI: 10.3390/cells10113113

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