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The somatic mutation landscape of normal gastric epithelium

2024-03-19

Abstract excerpt

<h4>ABSTRACT</h4> The landscapes of somatic mutation in normal cells inform on the processes of mutation and selection operative throughout life, permitting insight into normal ageing and the earliest stages of cancer development. Here, by whole-genome sequencing of 238 microdissections from 30 individuals, including 18 with gastric cancer, we elucidate the developmental trajectories of normal and malignant gastr...

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Literature Corpus work
fb166f3f-7941-528b-b5e7-f9a2f9ada0a9
DOI
10.1101/2024.03.17.585238
Open publication

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The somatic mutation landscape of normal gastric epitheliumDOI 10.1101/2024.03.17.585238
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