Article

The mutational landscape of normal human endometrial epithelium

2018-12-24

Abstract excerpt

All normal somatic cells are thought to acquire mutations. However, characterisation of the patterns and consequences of somatic mutation in normal tissues is limited. Uterine endometrium is a dynamic tissue that undergoes cyclical shedding and reconstitution and is lined by a gland-forming epithelium. Whole genome sequencing of normal endometrial glands showed that most are clonal cell populations derived from a...

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Literature Corpus work: b3b1968c-b3b2-5902-b38e-a76fad6ebe9b
DOI: 10.1101/505685

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