Article
Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine
2020-09-21
Abstract excerpt
<title>Abstract</title> <p><bold>Purpose</bold>: Cancer is a somatic evolutionary disease. Using multiregional whole exome sequencing, we tested the effect of somatic evolution on intratumoral heterogeneity and its putative clinical and biological implications in adenocarcinomas of the stomach and gastroesophageal junction (GC). <bold>Patients and Methods</bold>: The study comprised a prospective discovery cohort...
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Identifiers and source
- Literature Corpus work
- 111758ea-9f82-5398-aacc-8d2f4f5c25f4
- DOI
- 10.21203/rs.3.rs-62554/v2