Article

Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by a widely-used RT-PCR assay

2020-08-26

Abstract excerpt

We identify a mutation in the N gene of SARS-CoV-2 that adversely affects annealing of a commonly used RT-PCR primer; epidemiologic evidence suggests the virus retains pathogenicity and competence for spread. This reinforces the importance of using multiple targets, preferably in at least 2 genes, for robust SARS-CoV-2 detection. <h4>Article Summary Line</h4> A SARS-CoV-2 variant that occurs worldwide and has spr...

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Literature Corpus work: f94b2aed-3df0-5c98-9bed-377718ef24e2
DOI: 10.1101/2020.08.25.265074

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