Article

Identification of mutations in SARS-CoV-2 PCR primer regions

2022-07-22

Abstract excerpt

<title>Abstract</title> <p>Due to the constantly increasing number of mutations in the SARS-CoV-2 genome, concerns have emerged over the possibility of decreased diagnostic accuracy of reverse transcription-polymerase chain reaction (RT-PCR), the gold standard diagnostic test for SARS-CoV-2. We propose an analysis pipeline to discover genomic variations overlapping the target regions of commonly used PCR primer s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 026499d9-5fb1-5a85-8b03-fa90344ff543
DOI: 10.21203/rs.3.rs-1838361/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of mutations in SARS-CoV-2 PCR primer regionsDOI 10.21203/rs.3.rs-1838361/v1Read

Identification of mutations in SARS-CoV-2 PCR primer regions.Semantic proximity Read

Investigation of SARS-CoV-2 Variants at Primer Binding Sites in Diagnostic Platforms and the Effect on Laboratory Diagnostic SamplesSemantic proximity Read

SCOPE2: A Platform for Sars-COv-2 Primer covErage Evaluation.Semantic proximity Read

SARS-CoV-2 Variants Detection Using TaqMan SARS-CoV-2 Mutation Panel Molecular Genotyping AssaysSemantic proximity Read

Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by a widely-used RT-PCR assaySemantic proximity Read

Analysis of the potential impact of genomic variants in global SARS-CoV-2 genomes on molecular diagnostic assaysSemantic proximity Read

Presence of mismatches between diagnostic PCR assays and coronavirus SARS-CoV-2 genomeSemantic proximity Read

Evaluation of the effects of SARS-CoV-2 genetic mutations on diagnostic RT-PCR assaysSemantic proximity Read

A novel method for conserved sequence extraction with prospective mutation prediction for SARS-CoV-2 PCR primer design.Semantic proximity Read

assayM: a web application to monitor mutations in COVID-19 diagnostic assaysSemantic proximity Read

SARS-CoV-2 Evolution and Its Implications for RT-PCR Diagnostic Performance.Semantic proximity Read

Validation of RT-qPCR primers and probes for new and old variants of SARS-CoV-2 in a world scaleSemantic proximity Read