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Article

Identification of mutations in SARS-CoV-2 PCR primer regions.

Scientific reports - 4 Nov 2022

Mentes Anikó, Papp Krisztián, Visontai Dávid, Stéger József, Csabai István, Medgyes-Horváth Anna, Pipek Orsolya Anna

Abstract excerpt

Due to the constantly increasing number of mutations in the SARS-CoV-2 genome, concerns have emerged over the possibility of decreased diagnostic accuracy of reverse transcription-polymerase chain reaction (RT-PCR), the gold standard diagnostic test for SARS-CoV-2. We propose an analysis pipeline to discover genomic variations overlapping the target regions of commonly used PCR primer sets. We provide the list of...

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Identifiers

PMID: 36333366
DOI: 10.1038/s41598-022-21953-3
PMCID: PMC9636223

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