Article

Evaluation of the effects of SARS-CoV-2 genetic mutations on diagnostic RT-PCR assays

2021-01-20

Abstract excerpt

Several mutant strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are emerging. Mismatch(es) in primer/probe binding regions would decrease the detection sensitivity of the PCR test, thereby affecting the results of clinical testing. In this study, we conducted an in silico survey on SARS-CoV-2 sequence variability within the binding regions of primer/probe published by the Japan National Inst...

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Literature Corpus work: 77092c20-e7b0-53b0-83bc-ac0261d6fccf
DOI: 10.1101/2021.01.19.426622

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