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Analysis of the potential impact of genomic variants in global SARS-CoV-2 genomes on molecular diagnostic assays

9 Nov 2020

Abstract excerpt

An epidemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus diseases (C0VID-19) initially reported in Wuhan, China has rapidly emerged into a global pandemic affecting millions of people worldwide. Molecular detection of SARS-CoV-2 using reverse transcription polymerase chain reaction (RT-PCR) forms the mainstay in screening, diagnosis and epidemiology of the disease. Since the...

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PMID: 33181329
DOI: 10.1016/j.ijid.2020.10.086

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