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Investigation of SARS-CoV-2 Variants at Primer Binding Sites in Diagnostic Platforms and the Effect on Laboratory Diagnostic Samples

2026-04-23

Abstract excerpt

<title>Abstract</title> <p>As the COVID-19 pandemic continues to challenge global health systems, the reliability of diagnostic tests remains a critical concern. The most accurate way to identify SARS-CoV-2 infection is nucleic acid amplification tests (NAATs), especially real-time PCR (RT-PCR) assays. However, changes in SARS-CoV-2 primer and probe binding sites might compromise the accuracy of these diagnostic...

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Literature Corpus work: bda91291-df49-5bd3-91a9-682dcea42b72
DOI: 10.21203/rs.3.rs-8703149/v1

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