Article

Localised community circulation of SARS-CoV-2 viruses with an increased accumulation of single nucleotide polymorphisms that adversely affect the sensitivity of real-time reverse transcription assays targeting Nucleocapsid protein

2021-03-26

Abstract excerpt

<h4>Summary</h4> Currently the primary method for confirming acute SARS-CoV-2 infection is through the use of molecular assays that target highly conserved regions within the viral genome. Many, if not most of the diagnostic targets currently in use were produced early in the pandemic, using genomes sequenced and shared in early 2020. As viral diversity increases, mutations may arise in diagnostic target sites tha...

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Literature Corpus work: 6e803be9-f439-5e11-b1b2-df08ff370c39
DOI: 10.1101/2021.03.22.21254006

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Localised community circulation of SARS-CoV-2 viruses with an increased accumulation of single nucleotide polymorphisms that adversely affect the sensitivity of real-time reverse transcription assays targeting Nucleocapsid proteinDOI 10.1101/2021.03.22.21254006Read

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