Article

HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis

2021-07-29

Abstract excerpt

Carbohydrate Responsive Element-Binding Protein (ChREBP) is a carbohydrate sensing transcription factor that regulates both adaptive and maladaptive genomic responses in coordination of systemic fuel homeostasis. Genetic variants in the ChREBP locus associate with diverse metabolic traits in humans, including circulating lipids. To identify novel ChREBP-regulated hepatokines that contribute to its systemic metabol...

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Literature Corpus work: f943026a-7f06-5793-9e96-b691ffcb68ff
DOI: 10.1101/2021.07.29.454308

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