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Article

Adaptive and maladaptive roles for ChREBP in the liver and pancreatic islets.

The Journal of biological chemistry - 1 Jan 2000

Katz Liora S, Baumel-Alterzon Sharon, Scott Donald K, Herman Mark A

Abstract excerpt

Excessive sugar consumption is a contributor to the worldwide epidemic of cardiometabolic disease. Understanding mechanisms by which sugar is sensed and regulates metabolic processes may provide new opportunities to prevent and treat these epidemics. Carbohydrate Responsive-Element Binding Protein (ChREBP) is a sugar-sensing transcription factor that mediates genomic responses to changes in carbohydrate abundance...

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Identifiers

PMID: 33812993
DOI: 10.1016/j.jbc.2021.100623
PMCID: PMC8102921

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Adaptive and maladaptive roles for ChREBP in the liver and pancreatic islets.PMID 33812993Read ↗

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