Article

Hepatic HKDC1 Deletion Alleviates Western Diet-Induced MASH in Mice

2024-11-26

Abstract excerpt

The global prevalence of Metabolic dysfunction-associated steatohepatitis (MASH) has been rising sharply, closely mirroring the increasing rates of obesity and metabolic syndrome. MASH exhibits a strong sexual dimorphism where females are affected with more severe forms after menopause. Hexokinase domain-containing protein 1 (HKDC1) has recently been recognized for its role in liver diseases, where its expression...

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Literature Corpus work: f9c9e4f1-f587-5832-8669-09ddc9a10348
DOI: 10.1101/2024.11.26.625530

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